{"id":33145,"date":"2021-09-27T22:30:27","date_gmt":"2021-09-27T22:30:27","guid":{"rendered":"https:\/\/www.3dnatives.com\/en\/?p=33145"},"modified":"2021-09-27T22:38:43","modified_gmt":"2021-09-27T22:38:43","slug":"3d-printed-vaccine-patch-280920214","status":"publish","type":"post","link":"https:\/\/www.3dnatives.com\/en\/3d-printed-vaccine-patch-280920214\/","title":{"rendered":"3D-Printed Vaccine Patch Delivers Stronger Immune Response Than a Vaccine Shot"},"content":{"rendered":"

Since the emergence of this recent global pandemic, researchers across the globe have been coming up with new medical interventions to combat the virus. One such intervention has emerged through a collaboration between scientists from Stanford University and the University of North Carolina at Chapel Hill. The team of researchers has developed a 3D-printed vaccine patch that is capable of providing greater viral protection when compared to a traditional vaccine shot administered via syringe. Due to the skin’s vast immune cells, applying the vaccine patch directly to the skin allows for improved immune response.<\/p>\n

The team of microbiologists and chemical engineers are innovating existing RNA vaccines, like the Pfizer and Moderna COVID-19 vaccines, using microneedle patches. \u201cIn developing this technology, we hope to set the foundation for even more rapid global development of vaccines, at lower doses, in a pain- and anxiety-free manner<\/em>,\u201d said lead study author Joseph M. DeSimone, professor of translational medicine and chemical engineering at Stanford University and professor emeritus at UNC-Chapel Hill.<\/p>\n

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Microneedle vaccine patch that delivers a stronger immune response than a vaccine shot. (Photo Credit: University of North Carolina at Chapel Hill)<\/p><\/div>\n

The researchers used 3D-printed microneedles, lined up on a polymer patch that penetrates the surface of the skin just enough to deliver the vaccine. With the use of 3D printing, the microneedles can be customized to develop a myriad of vaccine patches for illnesses such as flu, measles, hepatitis, or COVID-19. \u201cOur approach allows us to directly 3D print the microneedles which gives us lots of design latitude for making the best microneedles from a performance and cost point-of-view,<\/em>\u201d explained lead study author Shaomin Tian, a researcher in the Department of Microbiology and Immunology in the UNC School of Medicine. The microneedles were created at the University of North Carolina at Chapel Hill using a CLIP prototype 3D printer that DeSimone invented and is produced by CARBON<\/a>, a Silicon Valley company where he is also a co-founder.<\/p>

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The results from the study show the vaccine patch caused a significant response from T-cells and antigen-specific antibodies which was 50 times greater than a traditional injection delivered under the skin. Furthermore, the 3D-printed vaccine patches do not require cold storage and circumvent the hurdle of needle-training professionals to administer vaccine shots. Since the patch can be self-administered the researchers also believe this will lead to more people taking the vaccine. Learn more about these vaccine patches HERE<\/a>.<\/p>\n

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The vaccine patch does not require cold storage and can be self-administered. (Photo Credit: UnSplash\/Bra\u0148o)<\/p><\/div>\n

What do you think of the 3D-printed vaccine patch? Let us know in a comment below or on our Facebook<\/a>\u00a0and\u00a0Twitter<\/a>\u00a0pages. Don\u2019t forget to sign up for our free weekly\u00a0newsletter<\/a>, with all the latest news in 3D printing delivered straight to your inbox!<\/p>\n

Cover Photo Credit: University of North Carolina at Chapel Hill<\/em><\/p>\n

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Since the emergence of this recent global pandemic, researchers across the globe have been coming up with new medical interventions to combat the virus. One such intervention has emerged through a collaboration between scientists from Stanford University and the University…<\/p>\n","protected":false},"author":6083,"featured_media":33151,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"content-type":"","footnotes":""},"categories":[32,1],"tags":[],"class_list":["post-33145","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-medical","category-news"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.3dnatives.com\/en\/wp-json\/wp\/v2\/posts\/33145","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.3dnatives.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.3dnatives.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.3dnatives.com\/en\/wp-json\/wp\/v2\/users\/6083"}],"replies":[{"embeddable":true,"href":"https:\/\/www.3dnatives.com\/en\/wp-json\/wp\/v2\/comments?post=33145"}],"version-history":[{"count":2,"href":"https:\/\/www.3dnatives.com\/en\/wp-json\/wp\/v2\/posts\/33145\/revisions"}],"predecessor-version":[{"id":33160,"href":"https:\/\/www.3dnatives.com\/en\/wp-json\/wp\/v2\/posts\/33145\/revisions\/33160"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.3dnatives.com\/en\/wp-json\/wp\/v2\/media\/33151"}],"wp:attachment":[{"href":"https:\/\/www.3dnatives.com\/en\/wp-json\/wp\/v2\/media?parent=33145"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.3dnatives.com\/en\/wp-json\/wp\/v2\/categories?post=33145"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.3dnatives.com\/en\/wp-json\/wp\/v2\/tags?post=33145"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}